Predictive Models for Neonatal Follow-Up Serum Bilirubin: Model Development and Validation.

ABSTRACT:

Background

Hyperbilirubinemia affects many newborn infants and, if not treated appropriately, can lead to irreversible brain injury.

Objective

This study aims to develop predictive models of follow-up total serum bilirubin measurement and to compare their accuracy with that of clinician predictions.

Methods

Subjects were patients born between June 2015 and June 2019 at 4 hospitals in Massachusetts. The prediction target was a follow-up total serum bilirubin measurement obtained <72 hours after a previous measurement. Birth before versus after February 2019 was used to generate a training set (27,428 target measurements) and a held-out test set (3320 measurements), respectively. Multiple supervised learning models were trained. To further assess model performance, pred

SUBMITTER: Chou JH 

PROVIDER: S-EPMC7661258 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature