Exosome-based immunotherapy: a promising approach for cancer treatment.

ABSTRACT: In the era of the rapid development of cancer immunotherapy, there is a high level of interest in the application of cell-released small vesicles that stimulate the immune system. As cell-derived nanovesicles, exosomes show great promise in cancer immunotherapy because of their immunogenicity and molecular transfer function. The cargoes carried on exosomes have been recently identified with improved technological advances and play functional roles in the regulation of immune responses. In particular, exosomes derived from tumor cells and immune cells exhibit unique composition profiles that are directly involved in anticancer immunotherapy. More importantly, exosomes can deliver their cargoes to targeted cells and thus influence the phenotype and immune-regulation functions of targeted cel

SUBMITTER: Xu Z 

PROVIDER: S-EPMC7661275 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature