Is the X chromosome a hot spot for sexually antagonistic polymorphisms? Biases in current empirical tests of classical theory.

ABSTRACT: Females and males carry nearly identical genomes, which can constrain the evolution of sexual dimorphism and generate conditions that are favourable for maintaining sexually antagonistic (SA) polymorphisms, in which alleles beneficial for one sex are deleterious for the other. An influential theoretical prediction, by Rice (Rice 1984 Evolution 38, 735-742), is that the X chromosome should be a 'hot spot' (i.e. enriched) for SA polymorphisms. While important caveats to Rice's theoretical prediction have since been highlighted (e.g. by Fry (2010) Evolution 64, 1510-1516), several empirical studies appear to support it. Here, we show that current tests of Rice's theory-most of which are based on quantitative genetic measures of fitness (co)variance-are frequently b

SUBMITTER: Ruzicka F 

PROVIDER: S-EPMC7661300 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature