Correct use of non-indexed eGFR for drug dosing and renal drug-related problems at hospital admission.

ABSTRACT:

Purpose

Two to seven percent of the German adult population has a renal impairment (RI) with an estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73m². This often remains unrecognized and adjustment of drug therapy is lacking. To determine renal function in clinical routine, the CKD-EPI equation is used to calculate an indexed eGFR (ml/min/1.73m²). For drug dosing, it has to be individualized to a non-indexed eGFR (ml/min) by the patient's body surface area. Here, we investigated the number of patients admitted to urological wards of a teaching hospital with RI between July and December 2016. Additionally, we correctly used the eGFR_non-indexed for drug and dosage adjustments and to analyse the use of renal risk drugs (RRD) and renal drug-rel

SUBMITTER: Seiberth S 

PROVIDER: S-EPMC7661404 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature