Covariables of Myocardial Function in Women and Men with Increased Body Mass Index.

ABSTRACT:

Introduction

Sex-difference in types of cardiac organ damage has been reported in subjects with increased body mass index (BMI). However less is known about sex-differences in left ventricular (LV) myocardial function assessed by global longitudinal strain (GLS) in these subjects.

Methods

493 subjects (mean age 47 ± 9 years, 61% women) with BMI > 27.0 kg/m² and without known cardiac disease underwent 24-hour (24h) ambulatory blood pressure (BP) recording, body composition analysis, carotid-femoral pulse wave velocity (PWV) measurement and echocardiography. LV peak systolic GLS was measured by two-dimensional speckle tracking echocardiography and LV ejection fraction (EF) by biplane Simpson's method. Insulin sensitivity was assessed by homeostatic model of insulin

SUBMITTER: Pristaj N 

PROVIDER: S-EPMC7661414 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature