Application of oblique nerve coaptation in autologous nerve transplantation.

ABSTRACT:

Background

Autologous nerve transplantation has become the gold standard for other nerve repair methods. But conventional epineurial sutures is prone to misaligned sutures, erroneous axonal growth, and unsatisfactory repair. Finding a new, more effective nerve coaptation method to improve the efficacy of peripheral nerve repair remains an urgent clinical challenge. In this study, the repair efficacies of oblique nerve coaptations for sciatic nerve injury at various angles were observed, providing a theoretical foundation for further clinical applications.

Methods

Sixty-four Sprague-Dawley rats were randomized into four groups of 16. The autologous nerve transplantation model was established by severing and rejoining in situ a 10-mm segment of the sciatic nerve trunk at the a

SUBMITTER: Ouyang L 

PROVIDER: S-EPMC7661904 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature