Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study.

ABSTRACT:

Background

Olfactory dysfunction is common in aging and associated with dementia and mortality. However, longitudinal studies tracking change in olfactory ability are scarce. We sought to identify predictors of interindividual differences in rate of olfactory identification change in aging.

Method

Participants were 1780 individuals, without dementia at baseline and with at least 2 olfactory assessments over 12 years of follow-up (mean age = 70.5 years; 61.9% female), from the Swedish National Study on Aging and Care in Kungsholmen (SNAC-K). Odor identification was assessed with the Sniffin' Sticks. We estimated the impact of demographic, health, and genetic factors on rate of olfactory change with linear mixed effect models.

Results

Advancing age, manufacturing profes

SUBMITTER: Ekstrom I 

PROVIDER: S-EPMC7662159 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature