Feeding brown fat: dietary phytochemicals targeting non-shivering thermogenesis to control body weight.

ABSTRACT: Excessive adipose accumulation, which is the main driver for the development of secondary metabolic complications, has reached epidemic proportions and combined pharmaceutical, educational and nutritional approaches are required to reverse the current rise in global obesity prevalence rates. Brown adipose tissue (BAT) is a unique organ able to dissipate energy and thus a promising target to enhance BMR to counteract a positive energy balance. In addition, active BAT might support body weight maintenance after weight loss to prevent/reduce relapse. Natural products deliver valuable bioactive compounds that have historically helped to alleviate disease symptoms. Interest in recent years has focused on identifying nutritional constituents that are able to induce BAT activity and thereby enhan

SUBMITTER: Horvath C 

PROVIDER: S-EPMC7663322 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature