New Lead Discovery of Herbicide Safener for Metolachlor Based on a Scaffold-Hopping Strategy.

ABSTRACT: The use of herbicide safeners can significantly alleviate herbicide injury to protect crop plants and expand the application scope of the existing herbicides in the field. Sanshools, which are well known as spices, are N-alkyl substituted compounds extracted from the Zanthoxylum species and have several essential physiological and pharmacological functions. Sanshools display excellent safener activity for the herbicide metolachlor in rice seedlings. However, the high cost of sanshools extraction and difficulties in the synthesis of their complicated chemical structures limit their utilization in agricultural fields. Thus, the present study designed and synthesized various N-alkyl amide derivatives via the scaffold-hopping strategy to solve the challenge of complicated

SUBMITTER: Deng X 

PROVIDER: S-EPMC7663620 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature