Defining Metaniches in the Oral Cavity According to Their Microbial Composition and Cytokine Profile.

ABSTRACT: The human oral microbiota consists of over 700 widespread taxa colonizing the oral cavity in several anatomically diverse oral niches. Lately, sequencing of the 16S rRNA genes has become an acknowledged, culture-independent method to characterize the oral microbiota. However, only a small amount of data are available concerning microbial differences between oral niches in periodontal health and disease. In the context of periodontitis, the cytokine expression in the gingival crevicular fluid has been studied in detail, whereas little is known about the cytokine profile in hard and soft tissue biofilms. In order to characterize oral niches in periodontal health, the oral microbiota and cytokine pattern were analyzed at seven different sites (plaque (P), gingival crevicular fluid (GCF), sali

SUBMITTER: Seidel CL 

PROVIDER: S-EPMC7663680 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature