Synthesis and molecular structure of perhalogenated rhenium-oxo corroles.

ABSTRACT: As part of our efforts to develop rhenium-oxo corroles as photosensitizers for oxygen sensing and photodynamic therapy, we investigated the potential β-perhalogenation of five ReO meso-tris(para-X-phenyl)corroles, Re[TpXPC](O) (X = CF₃, H, F, CH₃, and OCH₃), with elemental chlorine and bromine. With Cl₂, β-octachlorinated products Re[Cl₈TpXPC](O) were rapidly obtained for X = CF₃, H, and CH₃, but X = OCH₃ resulted in overchlorination on the meso-aryl groups. Full β-octabromination proved slower relative to Cu and Ir corroles, but the desired Re[Br₈TpXPC](O) products were finally obtained for X = H and F after a week at room temperature. For X = CH₃ and OCH₃, these condit

SUBMITTER: Alemayehu AB 

PROVIDER: S-EPMC7665048 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature