Gut Microbiota-targeted Interventions for Reducing the Incidence, Duration, and Severity of Respiratory Tract Infections in Healthy Non-elderly Adults.

ABSTRACT:

Introduction

Respiratory tract infections (RTI), such as those caused by influenza viruses and, more recently, the severe acute respiratory syndrome coronavirus-2, pose a significant burden to military health care systems and force readiness. The gut microbiota influences immune function, is malleable, and may provide a target for interventions aiming to reduce RTI burden. This narrative review summarizes existing evidence regarding the effectiveness of probiotics, prebiotics, and synbiotics, all of which are gut microbiota-targeted interventions, for reducing the burden of RTI in military-relevant populations (i.e., healthy non-elderly adults).

Materials and methods

A systematic search strategy was used to identify recent meta-analyses and systematic reviews of randomized c

SUBMITTER: Karl JP 

PROVIDER: S-EPMC7665594 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature