Risk of colorectal cancer in patients with diabetes mellitus: A Swedish nationwide cohort study.

ABSTRACT:

Background

Colorectal cancer (CRC) incidence is increasing among young adults below screening age, despite the effectiveness of screening in older populations. Individuals with diabetes mellitus are at increased risk of early-onset CRC. We aimed to determine how many years earlier than the general population patients with diabetes with/without family history of CRC reach the threshold risk at which CRC screening is recommended to the general population.

Methods and findings

A nationwide cohort study (follow-up:1964-2015) involving all Swedish residents born after 1931 and their parents was carried out using record linkage of Swedish Population Register, Cancer Registry, National Patient Register, and Multi-Generation Register. Of 12,614,256 individuals who were followed betw

SUBMITTER: Ali Khan U 

PROVIDER: S-EPMC7665813 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature