Association of Lower Urinary Tract Symptom Severity with Kidney Function among Community Dwelling Older Men.

ABSTRACT:

Purpose

Most international practice guidelines recommend screening for chronic kidney disease among older men with lower urinary tract symptoms. However, prior studies supporting these guidelines are insufficient due to incomplete assessments of kidney function and inadequate adjustment for confounding factors.

Materials and methods

We conducted a cross-sectional study among 5,530 American men older than 65 years in the multicenter Osteoporotic Fractures in Men Study. Chronic kidney disease was defined per international guidelines as estimated glomerular filtration rate less than 60 ml/minute/1.73 m² based on serum creatinine or cystatin C, or urinary albumin-to-creatinine ratio 30 mg/gm or greater. Lower urinary tract symptoms were assessed with the American Urol

SUBMITTER: Bauer SR 

PROVIDER: S-EPMC7665901 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature