Elastic Biomaterial Scaffold with Spatially Varying Adhesive Design.

ABSTRACT: In order to secure biomaterials to tissue surfaces, sutures or glues are commonly used. Of interest is the development of a biomaterial patch for applications in tissue engineering and regeneration that incorporates an adhesive component to simplify patch application and ensure sufficient adhesion. A separate region dedicated to fulfilling the specific requirements of an application such as mechanical support or tissue delivery is also desirable. Here, the design and fabrication of a unique patch are presented with distinct regions for adhesion and function, resulting in a biomaterial patch resembling the Band-Aid. The adhesive region contains a novel polymer, synthesized to incorporate a molecule capable of adhesion to tissue, dopamine. The desired polymer composition for patch developmen

SUBMITTER: Bannerman AD 

PROVIDER: S-EPMC7665997 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature