Association of Early-Life Trauma and Risk of Adverse Cardiovascular Outcomes in Young and Middle-aged Individuals With a History of Myocardial Infarction.

ABSTRACT: Compared with older patients, young adults with a history of myocardial infarction (MI) tend to have a higher burden of psychosocial adversity. Exposure to early-life stressors may contribute to the risk of adverse outcomes in this patient population, potentially through inflammatory pathways. To investigate the association of early-life trauma with adverse events and examine whether inflammation plays a role. This cohort study included patients aged 18 to 60 years with a verified history of MI in the past 8 months from a university-affiliated hospital network. Baseline data were collected from June 2011 to March 2016, and follow-up data were obtained through July 2019. Analysis began September 2019. Early-life trauma was assessed using the Early Trauma Inventory-Self Report short form (ET

SUBMITTER: Almuwaqqat Z 

PROVIDER: S-EPMC7666433 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature