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Radiomics Signatures of Cardiovascular Risk Factors in Cardiac MRI: Results From the UK Biobank.


ABSTRACT: Cardiovascular magnetic resonance (CMR) radiomics is a novel technique for advanced cardiac image phenotyping by analyzing multiple quantifiers of shape and tissue texture. In this paper, we assess, in the largest sample published to date, the performance of CMR radiomics models for identifying changes in cardiac structure and tissue texture due to cardiovascular risk factors. We evaluated five risk factor groups from the first 5,065 UK Biobank participants: hypertension (n = 1,394), diabetes (n = 243), high cholesterol (n = 779), current smoker (n = 320), and previous smoker (n = 1,394). Each group was randomly matched with an equal number of healthy comparators (without known cardiovascular disease or risk factors). Radiomics analysis was applied to sho

SUBMITTER: Cetin I 

PROVIDER: S-EPMC7667130 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature