Can dementia be predicted using olfactory identification test in the elderly? A Bayesian network analysis.

ABSTRACT:

Background

Previous studies suggest that olfactory dysfunction is associated with cognitive decline or dementia.

Objective

To find a potential association between the olfactory identification (OI) and dementia onset, and build a prediction model for dementia screening in the older population.

Methods

Nine hundred and forty-seven participants from the Shanghai Aging Study were analyzed. The participants were dementia-free and completed OI test using the Sniffin' Sticks Screening Test-12 at baseline. After an average of 4.9-year follow-up, 75 (8%) of the participants were diagnosed with incident dementia. Discrete Bayesian network (DBN) and multivariable logistic regression (MLR) models were used to explore the dependencies of the incident dementia on the baseline demog

SUBMITTER: Ding D 

PROVIDER: S-EPMC7667339 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature