Variability in body weight precedes diagnosis in dementia: A nationwide cohort study.

ABSTRACT:

Background

While there have been disagreements concerning whether obesity and increase in body weight elevate the risk of dementia, variability in body weight has been recently recognized as a new biometric associated with a high risk for a number of diseases. This nationwide, population-based cohort study examined the association between body weight variability and dementia.

Methods

A total of 2,812,245 adults (mean age, 51.7 years; standard deviation, 8.6) without a history of dementia who underwent at least three health examinations between 2005 and 2012 in a nationwide cohort were followed-up until the date of dementia diagnosis (based on prescribed drugs and disease code) or until 2016 (median follow-up duration, 5.38 years; interquartile range, 5.16-5.61). Cox regressi

SUBMITTER: Ha J 

PROVIDER: S-EPMC7667348 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature