Influence of primary tumor location and resection on survival in metastatic colorectal cancer.

ABSTRACT:

Background

Patients with right sided colorectal cancer are known to have a poorer prognosis than patients with left sided colorectal cancer, whatever the cancer stage. To this day, primary tumor resection (PTR) is still controversial in a metastatic, non resectable setting.

Aim

To explore the survival impact of PTR in patients with metastatic colorectal cancer (mCRC) depending on PTL.

Methods

We retrospectively collected data from all consecutive patients treated for mCRC at the Centre Georges Francois Leclerc Hospital. Univariate and multivariate Cox proportional hazard regression models were used to assess the influence of PTR on survival. We then evaluated the association between PTL and overall survival among patients who previously underwent or did not undergo PT

SUBMITTER: Tharin Z 

PROVIDER: S-EPMC7667454 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature