Therapeutic efficacy of umbilical cord-derived stem cells for diabetes mellitus: a meta-analysis study.

ABSTRACT:

Background

Stem cell therapy provides great hope for patients with diabetes mellitus (DM). DM is a seriously alarming metabolic disease characterized by hyperglycemia and β cell dysfunction. Efficient novel therapeutic modalities to treat DM are indeed warranted. Stem cells (SC) derived from the umbilical cord specifically provide several advantages and unique characteristics being a readily available non-invasive source, with an additional credit for their banking potential. This meta-analysis study aims to provide a focused assessment for therapeutic efficacy of umbilical cord (UC)-derived SC-transplantation, namely Wharton's jelly mesenchymal stem cells (WJ-MSCs) and umbilical cord blood (UCB) for DM.

Methods

The clinical efficacy was evaluated based on glycemic control s

SUBMITTER: Kassem DH 

PROVIDER: S-EPMC7667841 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature