Ontology highlight
ABSTRACT:
SUBMITTER: Zhao AY
PROVIDER: S-EPMC7667854 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Zhao Austin Y AY Brooks Allen F AF Raffel David M DM Stauff Jenelle J Arteaga Janna J Scott Peter J H PJH Shao Xia X
ACS medicinal chemistry letters 20201005 11
Radiolabeled guanidines such as <i>meta</i>-iodobenzylguanidine (MIBG) find utility in nuclear medicine as both diagnostic imaging agents and radiotherapeutics and, over the years, numerous methods for incorporating radionuclides into guanidines have been developed. In connection with a project developing new positron emission tomography (PET) radiotracers for cardiac sympathetic nerve density, we had cause to prepare [<sup>11</sup>C]3F-PHPOG. However, it quickly became apparent that radiolabeli ...[more]