Systematic Review with Meta-Analysis: Low-Level Alcohol Consumption and the Risk of Liver Cancer.

ABSTRACT:

Background/aims

Multiple meta-analyses and observational studies have reported that alcohol is a risk factor for liver cancer. However, whether there is a safe level of alcohol consumption remains unclear. We performed a systematic review and meta-analysis of the correlation between low-level alcohol consumption and the risk of liver cancer.

Methods

Nested case-control studies and cohort studies involving the general population published prior to July 2019 were searched. In total, 28 publications (31 cohorts) with 4,899 incident cases and 10,859 liver cancer-related deaths were included. The pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated.

Results

Compared with those with low levels of alcohol consumption, moderate and heavy drinkers (≥1 d

SUBMITTER: Park H 

PROVIDER: S-EPMC7667924 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature