Human immunoglobulin G responses to Cimex lectularius L. saliva.

ABSTRACT:

Aims

To investigate the immunoglobulin (Ig) G response after being fed upon by Cimex lectularius L.

Methods and results

Participants were fed upon by three male C lectularius insects weekly for a month. Blood was obtained before the feeding and at the last feeding, which was used for immunoblots against bed bug salivary gland extract, with antihuman Immunoglobulin G (IgG) secondary antibodies. No consistent IgG changes developed in 11 humans serially fed upon by C lectularius. Two participants had new IgG responses to proteins at molecular weights of approximately 12-13 kDa, and one had an IgG response to a protein at approximately 40 kDa. At the last study visit, more intense IgG bands to proteins at molecular weights of 12-13 kDa had developed in 55% of participants (6/11)

SUBMITTER: Sheele JM 

PROVIDER: S-EPMC7668222 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature