Male breast cancer in the United States: Treatment patterns and prognostic factors in the 21st century.

ABSTRACT:

Background

Male breast cancer (MBC) is a rare disease for which there is limited understanding of treatment patterns and prognostic factors.

Methods

Men with TNM stage I to stage III breast cancer diagnosed between 2004 and 2014 in the National Cancer Data Base were included. Trends in treatment modalities were described using the average annual percentage change (AAPC) and estimated using Joinpoint software for the analysis of trends. Kaplan-Meier curves and the multivariate Cox proportional hazards regression model were used to compare survival between subgroups and to identify prognostic factors.

Results

A total of 10,873 MBC cases were included, with a median age at diagnosis of 64 years. Breast-conserving surgery was performed in 24% of patients, and 70% of patie

SUBMITTER: Yadav S 

PROVIDER: S-EPMC7668385 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature