Effect of magnesium sulfate on renal colic pain: A PRISMA-compliant meta-analysis.

ABSTRACT:

Background

Magnesium sulfate (MgSO4) is widely used in analgesia for different conditions. Recent randomized controlled trials (RCTs) have evaluated the effects of MgSO4 on renal colic; however, this new evidence has not been synthesized. Thus, we conducted a systematic review and meta-analysis to assess the efficacy and safety of MgSO4 in comparison with control for renal colic.

Methods

PubMed, EMBASE, and Scopus databases were searched from inception to February 2020. We included RCTs that evaluated MgSO4 vs control for patients with renal colic. Data were independently extracted by 2 reviewers and synthesized using a random-effects model.

Results

Four studies with a total of 373 patients were analyzed. Intravenous MgSO4 15 to 50 mg/kg did not significantly reduce r

SUBMITTER: Chen LF 

PROVIDER: S-EPMC7668463 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature