International Trends in the Incidence of Cancer Among Adolescents and Young Adults.

ABSTRACT:

Background

Although adolescent and young adult (AYA) cancers represent a unique spectrum of malignancies, epidemiological studies of cancer incidence often group AYAs together with younger or older populations, obscuring patterns specific to this population.

Methods

We examined AYA cancer incidence trends in 41 countries over a 15-year period using the CI5plus database. Truncated age-standardized incidence rates were calculated and the annual percentage change was assessed, with statistical significance corresponding to a 95% confidence interval that does not include zero.

Results

From 1998 to 2012, the 41 included countries contributed a total of 1 846 588 cancer cases and 3.1 billion person-years among AYAs. Although statistically significant increases in the overal

SUBMITTER: Gupta S 

PROVIDER: S-EPMC7669231 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature