Beyond family-level adversities: Exploring the developmental timing of neighborhood disadvantage effects on the brain.

ABSTRACT: A growing literature suggests that adversity is associated with later altered brain function, particularly within the corticolimbic system that supports emotion processing and salience detection (e.g., amygdala, prefrontal cortex [PFC]). Although neighborhood socioeconomic disadvantage has been shown to predict maladaptive behavioral outcomes, particularly for boys, most of the research linking adversity to corticolimbic function has focused on family-level adversities. Moreover, although animal models and studies of normative brain development suggest that there may be sensitive periods during which adversity exerts stronger effects on corticolimbic development, little prospective evidence exists in humans. Using two low-income samples of boys (n = 167; n = 77), Census-derived neighborhoo

SUBMITTER: Gard AM 

PROVIDER: S-EPMC7669733 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature