Expression Partitioning of Duplicate Genes at Single Cell Resolution in Arabidopsis Roots.

ABSTRACT: Gene duplication is a key evolutionary phenomenon, prevalent in all organisms but particularly so in plants, where whole genome duplication (WGD; polyploidy) is a major force in genome evolution. Much effort has been expended in attempting to understand the evolution of duplicate genes, addressing such questions as why some paralog pairs rapidly return to single copy status whereas, in other pairs, both paralogs are retained and may diverge in expression pattern or function. The effect of a gene - its site of expression and thus the initial locus of its function - occurs at the level of a cell comprising a single cell type at a given state of the cell's development. Using Arabidopsis thaliana single cell transcriptomic data we categorized patterns of expression for 11,470 duplicate

SUBMITTER: Coate JE 

PROVIDER: S-EPMC7670048 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature