Effect of Genetic-Environmental Interaction on Chinese Childhood Myopia.

ABSTRACT:

Objective

The purpose of this study was to evaluate the effect of genetic-environmental interaction on myopia in Chinese children aged 6 to 9 years.

Methods

Students had the physical examination and were required to provide basic demographic information. Their families were asked to fill in a questionnaire concerning factors related to myopia. Multiple regression analysis was performed, and adjusted risk ratio values were calculated to assess the role between gene and environment. Value of the environmental and genetic index (EGI) was calculated to demonstrate the effect of genetic-environmental interaction on myopia.

Results

The prevalence of myopia maintained at a high level. EGI was calculated as 0.125 suggesting that genetic factors may play the 12.5% role in the

SUBMITTER: Zhang X 

PROVIDER: S-EPMC7670298 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature