Chronic obstructive pulmonary disease prevalence and prediction in a high-risk lung cancer screening population.

ABSTRACT:

Background

Chronic obstructive pulmonary disease (COPD) is an underdiagnosed condition sharing risk factors with lung cancer. Lung cancer screening may provide an opportunity to improve COPD diagnosis. Using Pan-Canadian Early Detection of Lung Cancer (PanCan) study data, the present study sought to determine the following: 1) What is the prevalence of COPD in a lung cancer screening population? 2) Can a model based on clinical and screening low-dose CT scan data predict the likelihood of COPD?

Methods

The single arm PanCan study recruited current or former smokers age 50-75 who had a calculated risk of lung cancer of at least 2% over 6 years. A baseline health questionnaire, spirometry, and low-dose CT scan were performed. CT scans were assessed by a radiologist for extent

SUBMITTER: Goffin JR 

PROVIDER: S-EPMC7670711 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature