Immunological Outcomes of Allergen-Specific Immunotherapy in Food Allergy.

ABSTRACT: IgE-mediated food allergies are caused by adverse immunologic responses to food proteins. Allergic reactions may present locally in different tissues such as skin, gastrointestinal and respiratory tract and may result is systemic life-threatening reactions. During the last decades, the prevalence of food allergies has significantly increased throughout the world, and considerable efforts have been made to develop curative therapies. Food allergen immunotherapy is a promising therapeutic approach for food allergies that is based on the administration of increasing doses of culprit food extracts, or purified, and sometime modified food allergens. Different routes of administration for food allergen immunotherapy including oral, sublingual, epicutaneous and subcutaneous regimens are being eva

SUBMITTER: Schoos AM 

PROVIDER: S-EPMC7670865 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature