Correlation-Centric Network (CCN) representation for microbial co-occurrence patterns: new insights for microbial ecology.

ABSTRACT: Mainstream studies of microbial community focused on critical organisms and their physiology. Recent advances in large-scale metagenome analysis projects initiated new researches in the complex correlations between large microbial communities. Specifically, previous studies focused on the nodes (i.e. species) of the Species-Centric Networks (SCNs). However, little was understood about the change of correlation between network members (i.e. edges of the SCNs) when the network was disturbed. Here, we introduced a Correlation-Centric Network (CCN) to the microbial research based on the concept of edge networks. In CCN, each node represented a species-species correlation, and edge represented the species shared by two correlations. In this research, we investigated the CCNs and their correspon

SUBMITTER: Yang P 

PROVIDER: S-EPMC7671402 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature