Genetic overlap between personality and risk for disordered gambling: evidence from a national community-based Australian twin study.

ABSTRACT: Using data from a large Australian twin sample we examined the extent to which genetic variation in the Big Three personality dimensions (positive emotionality, negative emotionality, and constraint) and their lower-order components explained genetic variation in the risk for disordered gambling (DG) among men and women. Genetic influences contributing to individual differences in normal-range personality traits explained over 40% of the genetic risk for DG, with a larger contribution among women than among men. The largest and most robust contributions came from the higher-order personality dimension of negative emotionality and its two lower-order dimensions of alienation and aggression. Surprisingly, low self-control was associated with the genetic risk for DG only among women, and risk

SUBMITTER: Slutske WS 

PROVIDER: S-EPMC7671713 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature