Predictability of CRP and D-Dimer levels for in-hospital outcomes and mortality of COVID-19.

ABSTRACT:

Background

Systemic inflammation elicited by a cytokine storm is considered a hallmark of coronavirus disease 2019 (COVID-19). This study aims to assess the clinical utility of the C-reactive protein (CRP) and D-Dimer levels for predicting in-hospital outcomes in COVID-19.

Methods

A retrospective cohort study was performed to determine the association of CRP and D-Dimer with the need for invasive mechanical ventilation (IMV), dialysis, upgrade to an intensive care unit (ICU) and mortality. Independent t-test and multivariate logistic regression analysis were performed to calculate mean differences and adjusted odds ratios (aOR) with its 95% confidence interval (CI), respectively.

Results

A total of 176 patients with confirmed COVID-19 diagnosis were included. On prese

SUBMITTER: Ullah W 

PROVIDER: S-EPMC7671719 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature