Identification of Genetic Biomarkers for Diagnosis of Myocardial Infarction Compared with Angina Patients.

ABSTRACT:

Background

Myocardial infarction (MI) is the most terrible appearance of cardiovascular disease. The incidence of heart failure, one of the complications of MI, has increased in the past few decades. Therefore, the identification of MI from angina patients and the determination of new diagnoses and therapies of MI are increasingly important. The present study was aimed at identifying differentially expressed genes and miRNAs as biomarkers for the clinical and prognosis factors of MI compared with angina using microarray data analysis.

Methods

Differentially expressed miRNAs and genes were manifested by GEO2R. The biological function of differentially expressed genes (DEGs) was examined by GO and KEGG. The construction of a protein-protein network was explored by STRING. cyto

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC7671815 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature