Adsorption therapy in critically ill with septic shock and acute kidney injury: a retrospective and prospective cohort study.

ABSTRACT:

Background

Haemoadsorption has been described as an effective way to control increased pro- and anti-inflammatory mediators ("cytokine storm") in septic shock patients. No prospective or randomised clinical study has yet confirmed these results. However, no study has yet prospectively specifically investigated patients in severe septic shock with sepsis-associated acute kidney injury (SA-AKI). Therefore, we aimed to examine whether haemoadsorption could influence intensive care unit (ICU) and hospital mortality in these patients. Furthermore, we examined the influence of haemoadsorption on length of stay in the ICU and therapeutic support.

Methods

Retrospective control group and prospective intervention group design in a tertiary hospital in central Europe (Germany). Interve

SUBMITTER: Schittek GA 

PROVIDER: S-EPMC7672170 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature