Physiologic responses to a staircase lung volume optimization maneuver in pediatric high-frequency oscillatory ventilation.

ABSTRACT:

Background

Titration of the continuous distending pressure during a staircase incremental-decremental pressure lung volume optimization maneuver in children on high-frequency oscillatory ventilation is traditionally driven by oxygenation and hemodynamic responses, although validity of these metrics has not been confirmed.

Methods

Respiratory inductance plethysmography values were used construct pressure-volume loops during the lung volume optimization maneuver. The maneuver outcome was evaluated by three independent investigators and labeled positive if there was an increase in respiratory inductance plethysmography values at the end of the incremental phase. Metrics for oxygenation (SpO₂, FiO₂), proximal pressure amplitude, tidal volume and transcutane

SUBMITTER: de Jager P 

PROVIDER: S-EPMC7672171 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature