Effect of an Emergency Department Care Bundle on 30-Day Hospital Discharge and Survival Among Elderly Patients With Acute Heart Failure: The ELISABETH Randomized Clinical Trial.

ABSTRACT:

Importance

Clinical guidelines for the early management of acute heart failure in the emergency department (ED) setting are based on only moderate levels of evidence, with subsequent low adherence to these guidelines.

Objective

To test the effect of an early guideline-recommended care bundle on short-term prognosis in older patients with acute heart failure in the ED.

Design, setting, and participants

Stepped-wedge cluster randomized trial in 15 EDs in France of 503 patients 75 years and older with a diagnosis of acute heart failure in the ED from December 2018 to September 2019 and followed up for 30 days until October 2019.

Interventions

A care bundle that included early intravenous nitrate boluses; management of precipitating factors, such as acute coronary

SUBMITTER: Freund Y 

PROVIDER: S-EPMC7672513 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature