Analysis and reporting of stratified cluster randomized trials-a systematic survey.

ABSTRACT:

Background

In order to correctly assess the effect of intervention from stratified cluster randomized trials (CRTs), it is necessary to adjust for both clustering and stratification, as failure to do so leads to misleading conclusions about the intervention effect. We have conducted a systematic survey to examine the current practices about analysis and reporting of stratified CRTs.

Method

We used the search terms to identify the stratified CRTs from MEDLINE since the inception to July 2019. In phase 1, we screened the title and abstract for English-only studies and selected, including the main results paper of the identified protocols, for the next phase. In phase 2, we screened the full text and selected studies for data abstraction. The data abstraction form was piloted a

SUBMITTER: Borhan S 

PROVIDER: S-EPMC7672868 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature