Histamine receptors and COVID-19.

ABSTRACT:

Objective

Reports that the over-the-counter histamine H₂ receptor antagonist famotidine could help treat the novel coronavirus disease (COVID-19) appeared from April 2020. We, therefore, examined reports on interactions between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and histamine receptor antagonists.

Methods

A systematic literature search was performed by 19 September 2020, and updated on 28 October 2020, in PubMed, Scopus, Cochrane Library and Google Scholar using (COVID-19 OR coronavirus OR SARS-CoV-2) AND (histamine antagonist OR famotidine OR cimetidine). ClinicalTrials.gov was searched for COVID-19 and (famotidine or histamine).

Results

Famotidine may be a useful addition in COVID-19 treatment, but the results from prospective ra

SUBMITTER: Ennis M 

PROVIDER: S-EPMC7673069 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature