Diaphragm Function Assessment During Spontaneous Breathing Trial in Patients with Neuromuscular Diseases.

ABSTRACT:

Introduction

The optimal time to discontinue patients from mechanical ventilation is critical as premature discontinuation as well as delayed weaning can result in complications. The literature on diaphragm function assessment during the weaning process in the intriguing subpopulation of critically ill neuromuscular disease patients is lacking.

Methods

Patients with neuromuscular diseases, on mechanical ventilation for more than 7 days, and who were ready for weaning were studied. During multiple T-piece trials over days, diaphragm function using ultrasound and diaphragm electrical activity (Edi peaks using NAVA catheter) was measured every 30 min till a successful 2 h weaning.

Results

A total of 18 patients were screened for eligibility over 5-month period and eight

SUBMITTER: Krishnakumar M 

PROVIDER: S-EPMC7673684 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature