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Dynamic light scattering imaging.

ABSTRACT: We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal sampling of speckle fluctuations and a comprehensive model to identify the dynamic scattering regime and obtain a quantitative image of the scatterer dynamics. It reveals errors in the traditional theory of laser Doppler flowmetry and laser speckle contrast imaging and provides guidance on the best model to use in cerebral blood flow imaging.

SUBMITTER: Postnov DD

PROVIDER: S-EPMC7673709 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Dynamic light scattering imaging.

Postnov Dmitry D DD Tang Jianbo J Erdener Sefik Evren SE Kılıç Kıvılcım K Boas David A DA

Science advances 20201106 45

We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal sampling of speckle fluctuations and a comprehensive model to identify the dynamic scattering regime and obtain a quantitative image of the scatterer dynamics. It reveals errors in the traditional theory of laser Doppler flowmetry and laser speckle contrast imaging and provides guidance on the best model to use in cerebr ...[more]

PMID: 33158865

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