Timing of Tracheostomy for Prolonged Respiratory Wean in Critically Ill Coronavirus Disease 2019 Patients: A Machine Learning Approach.

ABSTRACT:

Objectives

To propose the optimal timing to consider tracheostomy insertion for weaning of mechanically ventilated patients recovering from coronavirus disease 2019 pneumonia. We investigated the relationship between duration of mechanical ventilation prior to tracheostomy insertion and in-hospital mortality. In addition, we present a machine learning approach to facilitate decision-making.

Design

Prospective cohort study.

Setting

Guy's & St Thomas' Hospital, London, United Kingdom.

Patients

Consecutive patients admitted with acute respiratory failure secondary to coronavirus disease 2019 requiring mechanical ventilation between March 3, 2020, and May 5, 2020.

Interventions

Baseline characteristics and temporal trends in markers of disease severity were

SUBMITTER: Takhar A 

PROVIDER: S-EPMC7673767 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature