Influence of BDNF Genetic Polymorphisms in the Pathophysiology of Aging-related Diseases.

ABSTRACT: For the first time in history, most of the population has a life expectancy equal or greater than 60 years. By the year 2050, it is expected that the world population in that age range will reach 2000 million, an increase of 900 million with respect to 2015, which poses new challenges for health systems. In this way, it is relevant to analyze the most common diseases associated with the aging process, namely Alzheimer´s disease, Parkinson Disease and Type II Diabetes, some of which may have a common genetic component that can be detected before manifesting, in order to delay their progress. Genetic inheritance and epigenetics are factors that could be linked in the development of these pathologies. Some researchers indicate that the BDNF gene is a common factor of these diseases, an

SUBMITTER: Urbina-Varela R 

PROVIDER: S-EPMC7673859 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature