Prolonged Outbreak of Multidrug-Resistant Shigella sonnei Harboring bla_CTX-M-27 in Victoria, Australia.

ABSTRACT: In Australia, cases of shigellosis usually occur in returned travelers from regions of shigellosis endemicity or in men who have sex with men. Resistance to multiple antibiotics has significantly increased in Shigella sonnei isolates and represents a significant public health concern. We investigate an outbreak of multidrug-resistant S. sonnei in Victoria, Australia. We undertook whole-genome sequencing of 54 extended-spectrum-beta-lactamase (ESBL)-producing S. sonnei isolates received at the Microbiological Diagnostic Unit Public Health Laboratory between January 2019 and March 2020. The population structure and antimicrobial resistance profiles were identified by genomic analyses, with 73 previously characterized Australian S. sonnei isolates providing context

SUBMITTER: Ingle DJ 

PROVIDER: S-EPMC7674062 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature