Antibody dynamics to SARS-CoV-2 in asymptomatic COVID-19 infections.

ABSTRACT:

Background

The missing asymptomatic COVID-19 infections have been overlooked because of the imperfect sensitivity of the nucleic acid testing (NAT). Globally understanding the humoral immunity in asymptomatic carriers will provide scientific knowledge for developing serological tests, improving early identification, and implementing more rational control strategies against the pandemic.

Measure

Utilizing both NAT and commercial kits for serum IgM and IgG antibodies, we extensively screened 11 766 epidemiologically suspected individuals on enrollment and 63 asymptomatic individuals were detected and recruited. Sixty-three healthy individuals and 51 mild patients without any preexisting conditions were set as controls. Serum IgM and IgG profiles were further probed using a SAR

SUBMITTER: Lei Q 

PROVIDER: S-EPMC7675426 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature