Quantitative assessment of required separator fluid volume in multi-infusion settings.

ABSTRACT:

Background

Administering a separator fluid between incompatible solutions can optimize the use of intravenous lumens. Factors affecting the required separator fluid volume to safely separate incompatible solutions are unknown.

Methods

An intravenous tube (2-m, 2-mL, 6-French) containing methylene blue dye was flushed with separator fluid until a methylene blue concentration ⩽2% from initial was reached. Independent variables were administration rate, dye solvent (glucose 5% and NaCl 0.9%), and separator fluid. In the second part of the study, methylene blue, separator fluid, and eosin yellow were administered in various administration profiles using 2- and 4-mL (2 × 2 m, 4-mL, 6-French) intravenous tubes.

Results

Neither administration rate nor solvent affected the se

SUBMITTER: Doesburg F 

PROVIDER: S-EPMC7675775 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature