Epicardial adipose tissue is associated with extent of pneumonia and adverse outcomes in patients with COVID-19.

ABSTRACT:

Aim

We sought to examine the association of epicardial adipose tissue (EAT) quantified on chest computed tomography (CT) with the extent of pneumonia and adverse outcomes in patients with coronavirus disease 2019 (COVID-19).

Methods

We performed a post-hoc analysis of a prospective international registry comprising 109 consecutive patients (age 64 ± 16 years; 62% male) with laboratory-confirmed COVID-19 and noncontrast chest CT imaging. Using semi-automated software, we quantified the burden (%) of lung abnormalities associated with COVID-19 pneumonia. EAT volume (mL) and attenuation (Hounsfield units) were measured using deep learning software. The primary outcome was clinical deterioration (intensive care unit admission, invasive mechanical ventilation, or vasopressor ther

SUBMITTER: Grodecki K 

PROVIDER: S-EPMC7676319 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature