Diamond Light Source: contributions to SARS-CoV-2 biology and therapeutics.

ABSTRACT: The impact of COVID-19 on public health and the global economy has led to an unprecedented research response, with a major emphasis on the development of safe vaccines and drugs. However, effective, safe treatments typically take over a decade to develop and there are still no clinically approved therapies to treat highly pathogenic coronaviruses. Repurposing of known drugs can speed up development and this strategy, along with the use of biologicals (notably monoclonal antibody therapy) and vaccine development programmes remain the principal routes to dealing with the immediate impact of COVID-19. Nevertheless, the development of broadly-effective highly potent antivirals should be a major longer term goal. Structural biology has been applied with enormous effect, with key proteins struct

SUBMITTER: Walsh MA 

PROVIDER: S-EPMC7676326 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature